AS tarix : Fast and Optimal Sequence-to-Graph Alignment

Pesho Ivanov,Benjamin Bichsel,Harun Mustafa,André Kahles,Gunnar Rätsch,Martin Vechev

biorxiv（2020）

引用 15|浏览79

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摘要

Experimental evaluation of AS shows that it is 1–2 orders of magnitude faster than state-of-the-art optimal algorithms on the task of aligning Illumina reads to reference genome graphs. Implementations and evaluations are available at .

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关键词

Next-generation sequencing,Optimal alignment,Genome graph,Shortest path,A<sup>&#x22C6,</sup> algorithm

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