Evaluation of immunoglobulin M-specific capture enzyme-linked immunosorbent assays and commercial tests for flaviviruses diagnosis by a National Reference Laboratory

Journal of Virological Methods(2020)

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摘要
•The in house ZIKV IgM ELISA adapted here presented better performance than the commercial kit tested.•The in house DENV IgM ELISA was as sensitive as the commercial test analyzed, but considerably more specific.•In house YFV IgM ELISA was reliable and useful for the laboratorial diagnosis, especially in flavivirus endemic settings.
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关键词
Flaviviruses,Dengue,Zika,Yellow fever,ELISA,IgM,Commercial tests
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