Downregulation of IGF2 expression in third trimester placental tissues from Zika virus infected women in Brazil

Andréia A Suzukawa,Camila Zanluca,Natasha A N Jorge,Lucia de Noronha,Andrea C Koishi,Caroline B V de Paula,Patrícia Z Rebutini,Seigo Nagashima, Aruana F F Hansel-Frose,Vinícius S C Parreira,Juliano Bordignon,Margaret R MacDonald,Charles M Rice,Fabio Passetti,Claudia N Duarte Dos Santos

Journal of Infection（2020）

引用 2|浏览15

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摘要

•Transcriptome analysis of placental tissues from women infected by Zika virus•Zika infection downregulates placental insulin-like growth factor 2 (IGF2) expression•IGF2 downregulation was not observed for other flaviviruses infections in vitro•IGF2 protein was reduced in the decidual tissues of naturally infected women

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关键词

Zika virus,Placenta,Transcriptome,Insulin-Like Growth Factor II,Decidua

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