Relation Between Thyroid Function and Mortality in Patients With Chronic Heart Failure

•Subclinical thyroid dysfunction is very common in patients with chronic heart failure (∼10%).•There is a U-shaped relation between Thyroid-Stimulating Hormone and mortality.•Subclinical hypothyroidism is associated with worse outcome in univariable analysis, but the association disappears after adjustment for age and natriuretic peptide level.•There is a weak but significant association between increasing Thyroid-Stimulating Hormone and outcome in patients with heart failure with normal ejection fraction.