Magnetic bead-gold nanoparticle hybrids probe based on optically countable gold nanoparticles with dark-field microscope for T4 polynucleotide kinase activity assay

Zhao Yuanfang
Zhao Yuanfang
Tan Chunyan
Tan Chunyan
Sun Shuqing
Sun Shuqing
Tan Ying
Tan Ying

BIOSENSORS & BIOELECTRONICS, 2020.

Cited by: 0|Bibtex|Views0|DOI:https://doi.org/10.1016/j.bios.2019.111936
WOS

Abstract:

T4 polynucleotide kinase (T4 PNK) plays an essential role in DNA phosphorylation during the DNA repair process. Therefore, the sensitive, selective and convenient detection of T4 PNK activity is of great significance. In this work, we proposed a sensitive non-amplification strategy for the sensing of T4 PNK activity via dark field microsc...More

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