A novel aptasensor strategy for protein detection based on G-quadruplex and exonuclease III-aided recycling amplification

The detection of biomarkers is of great significance in the diagnosis of numerous diseases, especially cancer. Herein, we developed a sensitive and universal fluorescent aptasensor strategy based on magnetic beads, DNA G-quadruplex, and exonuclease III (Exo III). In the presence of a target protein, a label-free single strand DNA (ssDNA) ...More