Determination of in vitro and in vivo immune response to recombinant cholesterol oxidase from Mycobacterium tuberculosis
Immunology Letters(2020)
摘要
•Cholesterol oxidase from Mtb has the ability to induce an immune response in mice.•Cholesterol oxidase from Mtb favours the Th2-type response in mice.•Pro-inflammatory response induced by Mtb cholesterol oxidase is low.
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关键词
Mycobacterium tuberculosis,Cholesterol oxidase,Th1/Th2 response,Cytokines,Mouse peritoneal exudate cells
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