Determination of in vitro and in vivo immune response to recombinant cholesterol oxidase from Mycobacterium tuberculosis

Immunology Letters(2020)

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摘要
•Cholesterol oxidase from Mtb has the ability to induce an immune response in mice.•Cholesterol oxidase from Mtb favours the Th2-type response in mice.•Pro-inflammatory response induced by Mtb cholesterol oxidase is low.
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关键词
Mycobacterium tuberculosis,Cholesterol oxidase,Th1/Th2 response,Cytokines,Mouse peritoneal exudate cells
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