Effects of ω-3 PUFA and ascorbic acid combination on post-resuscitation myocardial function
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie（2021）
Abstract
•ω-3 PUFA and AA suppress lipid peroxidation; improve myocardial function.•ω-3 PUFA or AA treatment improves outcomes in a rat model of cardiac arrest.•A combination of ω-3 PUFA and AA therapy shows a synergy effect.•ω-3 PUFA or AA is a potential new therapeutic during cardiopulmonary resuscitation.
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Key words
CO,EF,MFI,MPI,MDA,PVD,ROSC,SOD,4-HNE
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