Increased neuronal activity in motor cortex reveals prominent calcium dyshomeostasis in tauopathy mice

Qian Wu, Yang Bai,Wei Li,Erin E Congdon,Wenke Liu,Yan Lin,Changyi Ji,Wen-Biao Gan,Einar M Sigurdsson

Neurobiology of Disease（2021）

引用 8|浏览31

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摘要

Perturbed neuronal Ca2+ homeostasis is implicated in Alzheimer's disease, which has primarily been demonstrated in mice with amyloid-β deposits but to a lesser and more variable extent in tauopathy models.

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关键词

Alzheimer's disease,Frontotemporal dementia,Tau,Antibody,Ca2+,Two-photon imaging,Mice

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