Intermittent repeated stress but not ketamine changes mice response to antidepressants

Milene Borsoi, Luis Eduardo D. Nunes, Amanda R. Barbosa,Mariana S. Lima, Isabelle Medeiros,Mariana A. Pranke,Camila B. Antonio,Stela M.K. Rates,Gilda A. Neves

Neuroscience Letters(2021)

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摘要
•Repeated ketamine anti-immobility effect lasted for 3 days after treatment.•Repeated intermittent stress impaired fluoxetine and imipramine anti-immobility effects.•Ketamine does not prevent stress-induced change in antidepressants’ effect.
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关键词
ACTH,CRF,FLU,FS,IMI,MDD,OF,PND,VEH
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