Phase I Expansion Study Of Xmt-1536, A Novel Napi2b-Targeting Antibody-Drug Conjugate (Adc): Preliminary Efficacy, Safety, And Biomarker Results In Patients With Previously Treated Metastatic Ovarian Cancer (Oc) Or Non-Small Cell Lung Cancer (Nsclc).

JOURNAL OF CLINICAL ONCOLOGY(2020)

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摘要
3549Background: XMT-1536 is a first-in-class ADC targeting the sodium-dependent phosphate transport protein NaPi2b, broadly expressed in NSCLC and ovarian cancer. XMT-1536 utilizes the Dolaflexin p...
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关键词
lung cancer,metastatic ovarian cancer,b-targeting,antibody-drug,non-small
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