The goblet appearance observed with endocytoscopy for prediction of histological mucin depletion and clinical relapse in patients with ulcerative colitis

Endoscopic mucosal healing is an important therapeutic goal in the management of ulcerative colitis (UC). However, some patients clinically relapse in the short term despite endoscopic mucosal healing was achieved. Recently, it has been reported that the histological mucin depletion was an independent clinically relapse factor of patients with an Mayo endoscopic score (MES) of 0.