THU0481 THE PREVALENCE OF CHRONIC MUSCULOSKELETAL PAIN IN PATIENTS WITH ULCERATIVE COLITIS IN COMPARISON TO CONTROLS FROM THE GENERAL POPULATION: A CROSS-SECTIONAL STUDY
Annals of the Rheumatic Diseases(2020)
摘要
Background: Musculoskeletal symptoms are common in patients with ulcerative colitis (UC) but the knowledge of the prevalence of chronic regional pain (ChRP) and chronic widespread pain (ChWP) in patients with UC is scarce. Objectives: To compare the prevalence of ChRP, ChWP and chronic pain in different body locations in patients with UC with controls from the general population and to investigate if disease activity in UC is related to chronic pain. Methods: From a national inflammatory bowel disease (IBD) Register (SWIBREG), all living patients with a confirmed UC diagnosis, aged 20-74 years (n=1134), who were residents in two counties in Northern Sweden were posted a validated questionnaire. Persons from the general population from a previous study (1) using the same questionnaires was used as controls (n=3867). The questionnaire comprises demography, history of pain and body localisation of pain. The disease activity of UC was measured by Patient- Simple Clinical Colitis Activity Index (P-SCCAI). ChRP and ChWP was defined as having pain for at least three months the last year. ChWP was defined as having pain on both left and right side of the body and both above and below the waist, and in the axial part of the body. Results: The response rate for the patients with UC was 49.0% and for the controls 62.7%. The patients were older than the controls (mean age 52.8 vs 46.5 years; p 5 (n=121) reported more ChWP than patients with P-SSCAI Conclusion: Patients with UC reported more chronic pain than controls from the general population, especially from the lower back and hip region. Higher UC disease activity was associated with more pain in all body regions. References: [1]Bergman S, Herrstrom P, Hogstrom K, Petersson IF, Svensson B, Jacobsson LT. Chronic musculoskeletal pain, prevalence rates, and sociodemographic associations in a swedish population study. J Rheumatol 2001;28:1369-77. Disclosure of Interests: : Nina Pettersson: None declared, Fredrik Kragsbjerg: None declared, Arvid Hamrin: None declared, Stefan Bergman: None declared, Helena Forsblad-d’Elia Grant/research support from: Unrestricted grant from Novartis., Consultant of: Advisory Board Fees from Sandoz, Novartis, and Abbvie, Pontus Karling: None declared
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