A hybrid correcting method considering heterozygous variations by a comprehensive probabilistic model

Jiaqi Liu
Jiaqi Liu
Xiao Xiao
Xiao Xiao
Xin Lai
Xin Lai
Daocheng Dai
Daocheng Dai
Juan Wang
Juan Wang
Zhimin Li
Zhimin Li

BMC genomics, pp. 7532020.

Cited by: 0|Bibtex|Views11|DOI:https://doi.org/10.1186/s12864-020-07008-9
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Other Links: pubmed.ncbi.nlm.nih.gov|academic.microsoft.com

Abstract:

To verify the performance of our method, we selected Canu and Jabba to compare with QIHC in several aspects. As a hybrid correction method, we first conducted a groups of experiments under different coverages of the next-generation sequencing data. QIHC is far ahead of Jabba on accuracy. Meanwhile, we varied the coverages of the third gen...More

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