Asymmetric Epoxidation of alpha,beta-Unsaturated Ketones Catalyzed by Chiral Iron Complexes of (R,R)-3,4-Diaminopyrrolidine Derived N4-Ligands with Camphorsulfonyl Sidearms

Yuanfeng Li,Yuecheng Zhang,Hong-Yu Zhang,Ya-Ping Han,Jiquan Zhao

ASIAN JOURNAL OF ORGANIC CHEMISTRY（2020）

引用 4|浏览5

暂无评分

摘要

Three (R,R)-3,4-diaminopyrrolidine-based chiral N-4 ligands and corresponding iron complexes were synthesized. The complexes were applied to the asymmetric epoxidation of various alpha,beta-unsaturated ketones with H2O2 as an oxidant and carboxylic acid as auxiliary. Good to excellent enantioselectivity (up to 97%) was achieved in the case of 2,2-dimethylbutyric acid as an auxiliary.

查看译文

关键词

Asymmetric epoxidation,(R,R)-3,4-Diaminopyrrolidine,Non-heme,Iron,Camphorsulfonyl sidearm,alpha,beta-Unsaturated ketones

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要