Sirt7 Deficiency Attenuates Vascular Lesion Development by Suprresssion of Micro-RNA-Dependent Proliferation of Vsmcs

Yuichi Kimura,Yasuhiro Izumiya,Satoshi Araki,Toshifumi Ishida, Satoru Yamamura,Shinsuke Hanatani,Kenichi Tsujita

CIRCULATION（2017）

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摘要

Background: Sirt7 is a latest identified sirtuin and has important roles in various pathological conditions, including cancer progression and metabolic disorders. We have recently shown that Sirt7 ...

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关键词

Vascular disease,Atherosclerosis,Abdominal aortic aneurysm,Remodeling,Smooth muscle regulation

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