Clearance of ctDNA in triple-negative and HER2-positive breast cancer patients during neoadjuvant treatment is correlated with pathologic complete response.

Nikaoly Ciriaco,Esther Zamora,Santiago Escrivá-de-Romaní, Ignacio Miranda Gómez,José Jiménez Flores,Cristina Saura,Hillary Sloane, Anna Starus,Johannes Fredebohm, Lucy Georgieva, Graham Speight,Frederick Jones,Santiago Ramón Y Cajal,Martín Espinosa-Bravo,Vicente Peg

CLINICAL CANCER RESEARCH（2022）

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摘要

These findings prompt further research of the value of ctDNA for non-invasive prediction of clinical/pathological response, raising the possibility of sparing surgery following NAC in selected BC patients.

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关键词

ctdna,breast cancer,neoadjuvant treatment,triple-negative

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