Elongated neutrophil-derived structures are blood-borne microparticles formed by rolling neutrophils during sepsis
The Journal of experimental medicine, 2021.
Rolling neutrophils form tethers with submicron diameters. Here, we report that these tethers detach, forming elongated neutrophil-derived structures (ENDS) in the vessel lumen. We studied ENDS formation in mice and humans in vitro and in vivo. ENDS do not contain mitochondria, endoplasmic reticulum, or DNA, but are enriched for S100A8, S...More
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