Multiple Sequence Alignment for Large Heterogeneous Datasets Using SATé, PASTA, and UPP

Methods in molecular biology (Clifton, N.J.), pp. 99-119, 2021.

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Abstract:

The estimation of very large multiple sequence alignments is a challenging problem that requires special techniques in order to achieve high accuracy. Here we describe two software packages-PASTA and UPP-for constructing alignments on large and ultra-large datasets. Both methods have been able to produce highly accurate alignments on 1,00...More

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