Emerging Topics In Heart Failure: Interventional Heart Failure Therapies

Treatment of Secondary Mitral Regurgitation Before considering percutaneous treatment of mitral regurgitation (MR) for patients with heart failure (HF) with reduced ejection fraction (HFrEF) and severe MR, we recommend that guideline-directed medical therapy be optimized, including cardiac resynchronization therapy and revascularization, where appropriate. The use of the edge-to-edge device could benefit patients with moderately severe or severe secondary MR (effective regurgitant orifice area [EROA] ≥ 30 mm2 and/or regurgitant volume \u003e 45 mL) with a left ventricular ejection fraction (LVEF) [...]