Modulation of TRPC Store‐operated Channels by Orai and STIM Proteins

Dmitrii Kolesnikov, Liubov Glushankova,Anton Skopin,Konstantin Gusev,Leonid Shuyskiy,Svetlana Sozonova,Elena Kaznacheyeva,Alexey Shalygin

FASEB JOURNAL（2020）

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摘要

Store‐operated calcium entry is significant pathway of calcium concentration rise in cytoplasm. The main players in this process are Orai store‐operated channels, which are activated directly by STIM calcium sensors. Data on participation of TRPC channels in store‐operated calcium entry is controversial.

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