Evaluation of crude adult Ascaris suum intestinal tract homogenate in inducing protective IgG production against A. suum larvae in BALB/c mice

Mark John Girasol, Lordom Reno Grecia,Jillean Camille Fabi, Andro Jibreel Fernandez, Jerieka Nicole Isabela Fernandez,Gabrielle Flores, Rafael Flores, Enrique Luis Fontanilla, Paolo Joaquin Fragante, Virgilio Clemente Genuino, Stacey Caryl Go, Israel Gotico, Mary Eurielle Gregorio, Manuel Angelo Grino, Patricia Marie Guevarra, Safrollah Guinal, Raissa Guldam, Gian Carlo Infante, John Paul Jalandoni, Ian Gabriel Juyad,Cynthia Valencia,Irma Makalinao,Pilarita Tongol-Rivera,Ailyn Manglicmot-Yabes

Experimental Parasitology（2021）

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摘要

Globally, ascariasis ranks as the second leading intestinal helminth infection. However, progress in developing better control strategies, such as vaccines, remains slow-paced. This study aims to measure antibody production and parasite load in male BALB/c mice immunized with crude Ascaris suum intestinal tract homogenate.

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关键词

Ascariasis,Ascaris suum,Soil-transmitted helminthiasis,Neglected tropical disease,Vaccine,Immunoparasitology

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