Exploring the safety and efficacy of adding ketoconazole to tacrolimus in pediatric renal transplant immunosuppression.
World journal of transplantation(2020)
摘要
Patients experienced an effective dose-reduction of tacrolimus with the administration of ketoconazole. There was no relevant variations in tacrolimus serum levels, number of rejections, or significant liver toxicity. The strategy allowed a cost reduction in pediatric immunosuppressive therapy.
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关键词
Chart review,Immunosuppression,Ketoconazole,Pediatric,Tacrolimus,Transplant
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