Cutaneous Intralymphatic Anaplastic Lymphoma Kinase-Negative Anaplastic Large-Cell Lymphoma Arising In A Patient With Multiple Rounds Of Breast Implants
JOURNAL OF CUTANEOUS PATHOLOGY(2021)
摘要
Primary cutaneous anaplastic large-cell lymphoma and breast implant-associated ALCL (BIA-ALCL) are rare subtypes of anaplastic lymphoma kinase (ALK)-negative ALCLs originating from skin and breast implants, respectively. Herein, we report a unique case of cutaneous ALK-negative ALCL occurring in the skin of left medial breast from a patient with multiple rounds of bilateral breast implants and a history of breast carcinoma. The lymphoma cells are entirely confined to the lymphatic channels in the dermis, and the patient has no other areas of skin abnormality, no lymphadenopathy, peri-implant fluid accumulation, or masses from the bilateral capsules of implants. The differential diagnosis and its relationship with breast implants are further explored.
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关键词
anaplastic large‐, cell lymphoma, anaplastic lymphoma kinase, breast implant
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