Potential Roles of the Glass Transition Temperature o wf PLGA Microparticles in Drug Release Kinetics

Farrokh Sharifi
Farrokh Sharifi
John Garner
John Garner
Sarah Skidmore
Sarah Skidmore
Haesun Park
Haesun Park
Young Kuk Jhon
Young Kuk Jhon
Bin Qin
Bin Qin

Molecular pharmaceutics, 2020.

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Abstract:

Poly(lactic--glycolic acid) (PLGA) has been used for long-acting injectable drug delivery systems for more than 30 years. The factors affecting the properties of PLGA formulations are still not clearly understood. The drug release kinetics of PLGA microparticles are influenced by many parameters associated with the formulation composition...More

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