Airway Elastin is Increased in Severe Asthma and Relates to Proximal Wall Area: Histological and Computed Tomography Findings from the U‐BIOPRED Severe Asthma Study

Susan J. Wilson,Jonathan A. Ward, Helen M. Pickett,Simonetta Baldi,Ana R. Sousa,Peter J. Sterk,Kian Fan Chung,Ratko Djukanovic,Barbro Dahlen,Bo Billing,Dominick Shaw,Norbert Krug,Thomas Sandstrom,Christopher Brightling,Peter H. Howarth

Clinical & experimental allergy/Clinical and experimental allergy（2021）

引用 9|浏览54

暂无评分

摘要

Airway remodelling, which may include goblet cell hyperplasia / hypertrophy, changes in epithelial integrity, accumulation of extracellular matrix components, smooth muscle hypertrophy and thickening of the lamina reticularis, is a feature of severe asthma and contributes to the clinical phenotype.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要