LIPOPROTEIN LIPASE GENE POLYMORPHISM rs320 AND METABOLIC SYNDROME N NATIVE PEOPLE OF YAKUT

The aim of the study was investigation the relationship of allelic variants and genotypes of the rs 320 polymorphism of the LPL gene with the metabolic syndrome and its components in adult population of the Yakut ethnic group. In the studied group, it was not possible to establish a direct connection between the allelic variants, the genotypes of the LPL rs320 gene with the metabolic syndrome and its components. However, it is important to note individuals with the TT genotype had somewhat higher level of triglycerides in the blood. It may be associated with a small sample size. We assume that the T allele is associated with low enzyme activity in this population, and plays a key role in the development of diseases associated with metabolic disorders.