Influence of gamma radiation on Amphotericin B incorporated in PVP hydrogel as an alternative treatment for cutaneous leishmaniosis

•Leishmaniasis control in endemic countries is still a growing problem.•The variety of drugs available to treat leishmania is relatively limited.•Amph-B hydrogel can be applied as an alternative treatment for cutaneous leishmaniasis.•The hydrogel protects from microorganisms, keeping the wound bed moist,.•Local treatment avoids toxicity in patients with cardiac arrhythmia or renal dysfunction.