Isolation And Identification Of Tyrosinase Inhibitors From Marine Algae Enteromorpha Sp
LETTERS IN ORGANIC CHEMISTRY(2021)
摘要
The extract of marine green algae Enteromorpha sp. was evaluated in vitro for inhibitory activity against mushroom tyrosinase enzyme. The principle active agents i.e. coumarin; 4-hydroxy-coumarin (1) and two sterols; ergosta-5,7,22-trien-3 beta-ol (2) & ergosterol peroxide (3) were isolated for the first time, from a crude methanol extract of Enteromorpha sp. showing anti-tyrosinase activity. Their structures were elucidated by IR, extensive NMR spectroscopy, LC-ESI-MS, Single crystal X-ray diffraction techniques. Thus, Enteromorpha sp. can be an alternative edible anti-tyrosinase agent.
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关键词
Marine natural products, anti-tyrosinase activity, Enteromorpha sp., Ulvaceae, marine algae
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