Noninvasive Assessment Of Cytokine And Antimicrobial Peptide Levels In Hidradenitis Suppurativa Using Transdermal Analysis Patches

Most of the currently available cytokine and antimicrobial peptide (AMP) expression data from Hidradenitis suppurativa (HS) lesions have been obtained through painful, invasive sampling techniques such as biopsies. In contrast, a Transdermal Analysis Patch (TAP, FibroTx, Tallinn, Estonia) captures and measures biomarkers at the skin surface and as such represents a novel, non-invasive, and patient-friendly diagnostic tool for skin biomarker detection. The aim of this study was to measure the levels of several cytokines and AMPs in both lesional and uninvolved skin of HS patients and site-matched skin of controls using TAPs.