Testing for lynch syndrome in people with endometrial cancer using immunohistochemistry and microsatellite instability-based testing strategies – A systematic review of test accuracy

•People with Lynch syndrome are at an increased risk of a range of cancers.•This is the first systematic review of test accuracy of testing for Lynch syndrome in women with endomentrial cancer.•The sensitivity of the index tests were generally high, though most studies had much lower specificity.•There was no evidence that test accuracy differed between testing strategies.