Abstract 11795: Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-

Ryo Kurosawa,Kimio Satoh,Nobuhiro Kikuchi,Taijyu Satoh,Junichi Omura,Masamichi Nogi,Shinichiro Sunamura,Mohammad Abdul Hai Siddique,M. Elias Al-Mamun,Nobuhiro Yaoita,Toru Shimizu,Hiroaki Shimokawa

Circulation（2019）

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摘要

Introduction: Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation of pulmonary artery smooth muscle cells (PASMCs) accompanying increased production of inflammatory fac...

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关键词

celastramycin,pulmonary arterial hypertension,novel therapeutic agent,arterial hypertension,high-throughput

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