Mechanisms of Resistance and Determinants of Response of the GPRC5D-Targeting T-Cell Redirecting Bispecific Antibody JNJ-7564 in Multiple Myeloma

Christie P. M. Verkleij,Marloes Broekmans,Amy Wong,Sonja Zweegman,Raluca Verona,Homer Adams,Tuna Mutis,Niels W. C. J. van de Donk

BLOOD（2020）

引用 5|浏览25

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摘要

Introduction: New immunotherapies directed against CD38, SLAMF7 or BCMA have significantly improved the outcome of multiple myeloma (MM) patients. However, most patients eventually relapse, underscoring the need for additional immunotherapeutic targets.

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关键词

multiple myeloma,antibody,d-targeting,t-cell

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