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Evinacumab Lowers Ldl-C In Patients With Homozygous Familial Hypercholesterolemia Irrespective Of Background Lipid-Lowering Medication

Frederick J. Raal,Robert S. Rosenson,Laurens F. Reeskamp,G. Kees Hovingh,John J. Kastelein,Paolo Rubba,Shazia Ali,Poulabi Banerjee,Kuo-Chen Chan, Nagwa Khilla,Jennifer Mcginniss,Robert Pordy,Yi Zhang,Daniel Gaudet

Circulation（2020）

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摘要
Background: Homozygous familial hypercholesterolemia (HoFH) is characterized by very premature atherosclerotic cardiovascular disease due to profoundly elevated levels of LDL-C. Attempts to lower L...
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