Monoterpene Alkaloid Glycosides From The Leaves Of Nauclea Orientalis

Four new monoterpene alkaloid glycosides, kanluaengosides A-D (1, 2, 8, and 9), were isolated from the leaves of Nauclea orientalis. Additionally, the 12 known compounds were identified as (3S)-pumiloside (3), strictosamide (4), vincosamide (5), 10-hydroxystictosamide (6), 10-hydroxyvincoside lactam (7), paratunamide B (10), paratunamide C (11), vitexin (12), vicenin-2 (13), kaempferol 3-O-rutinoside (14), rutin (15) and eugenyl beta-rutinoside (16). Their structures were determined based on the physical data and the spectroscopic evidence including 1D and 2D NMR experiments.