Abstract 14164: Reduction in ApoB Levels After a Single Dose of MEDI6012 in Subjects Receiving High-Intensity Statin Therapy Suggests Enhancement of Low-Density Lipoprotein Receptor-Mediated Reverse Cholesterol Transport
Circulation(2017)
摘要
Introduction: MEDI6012 is recombinant human lecithin-cholesterol acyltransferase (rhLCAT). LCAT is the rate-limiting enzyme in reverse cholesterol transport (RCT) that facilitates the esterificatio...
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Coronary artery disease
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