Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs

Konstantin Byrgazov,Marianne Kraus,Andrej Besse,Ana Slipicevic,Fredrik Lehmann,Christoph Driessen,Lenka Besse

Leukemia Research（2021）

引用 7|浏览21

暂无评分

摘要

•High ABCB1 expression still predicts shorter survival in myeloma.•ABCB1 expression is elevated in myeloma progressing to extramedullary disease.•Melflufen and bortezomib are the most promising in ABCB1-positive high risk myeloma.

查看译文

关键词

Myeloma,Drug resistance,Proteasome inhibitors,MDR1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要