Autoantibodies against C5aR1, C3aR1, CXCR3, and CXCR4 are decreased in primary Sjogren’s syndrome

Xiaoyang Yue,Fengyuan Deng,Juan Chen,Junping Yin,Junfeng Zheng,Yan Chen,Qiaoniang Huang,Xing Gao,Zuguo Liu,Jiao Luo,Antje Müller,Harald Heidecke,Gabriela Riemekasten,Frank Petersen,Xinhua Yu

Molecular Immunology（2021）

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摘要

•Autoantibodies to C5aR1, C3aR1, CXCR3 and CXCR4 are decresed in pSS and RA.•Autoantibodies to CXCR3 and CXCR4 correlate with circulating lymphocytes in pSS.•Correlation signature of anti-GPCR antibodies is associateded to lung invovlement in pSS.

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关键词

AT1R,aabs,CXCR3,CXCR4,C3aR1,C5aR1,ETAR,ESSDAI,GPCR,HD,M3R,pSS,PAR1,PAR2,VEGFR1,VEGFR2,β1AR,β2AR

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