Metabolic Adaptations Of Human Alveolar Macrophages Upon Activation By Lipopolysaccharide In Vivo

Macrophages are versatile cells, with a repertoire of functions that regulate pro-inflammatory and anti-inflammatory responses, tissue repair, remodeling and homeostasis. These functions not only rely on the type of immunological challenge but are also highly dependent on the tissue-specific microenvironment. Alveolar macrophages (AMs) play an important role in the regulation of inflammation in the lung.