Increased SGK1 Activity Potentiates Mineralocorticoid/nacl-Induced Kidney Injury.
American journal of physiology Renal physiology/American journal of physiology Renal physiology(2021)
摘要
Increased activity of protein kinase SGK1 may be a risk factor for accelerated renal damage. SGK1 expression could be a marker for rapid progression toward CKD and a potential therapeutic target to slow down the process.
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关键词
aldosterone,chronic kidney disease,fibrosis,mineralocorticoid receptor,serum and glucocorticoid-regulated kinase 1
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