Expérience africaine monocentrique de la prise en charge personnalisée des cancers du sein à Abidjan : défis et perspectives

Aim. - To present the results of the personalized care of Ivorian women suffering from breast cancer since the advent of immunohistochemistry in Cote d'Ivoire. Methods. - We carried out a single-center retrospective study at the Yopougon university hospital from January 2014 to December 2018. All women's breast cancer with complementary immunohistochemistry and treated at the Yopougon hospital center were selected. Standard descriptive statistical tests were used to describe patient and tumor characteristics, and univariate and multivariate analyzes were performed with a statistical significance set at a P-value of 0.05 using SPSS version 20.0. Results. - The mean age of women is 48.27 years, SD (11.92). 50.88 % of the tumors were hormone dependent. The triple negative subgroup was the most represented (43.28 %) followed by luminal A (35.42 %). Conservative treatment represented 18.51 % of cases. In the univariate analysis, the risk of developing a hormone-dependent cancer is statistically significant respectively in women with an education level removed OR = 1.98 (P < 0.015) and with a wealthy salary OR = 1.85 (P < 0.009). On the other hand, the high level of education (OR = 0.44; P < 0.005), and the well-off salary condition (OR = 0.59; P < 0.024) would be protective factors for the development of triple negative breast cancer. All these factors are not significant in multivariate analysis, whether for hormone-dependent or triple negative tumors. Conclusion. - The personalized care of breast cancer in our African context remains difficult and must take into account several medical and extra-medical parameters. (c) 2021 Elsevier Masson SAS. All rights reserved.