BAKERS YEAST CATALYZED AND ULTRASOUND ACCELERATED SYNTHESIS OF 2-AMINO-2-CHROMENES

In the present work, bakers yeast catalyzed efficient synthesis of 2-amino-2-chromenes in methanol is presented. Here the ultrasonication has dual role i.e. as a source of energy for the reaction and tool for the disruption of the yeast cells. The cyclocondensation has been essentially carried under neutral conditions, thus reducing the possibility of unwanted side reactions.