Application of Obatoclax in preparation of HIV-1 latent infection reversal agent

The invention provides an application of Obatoclax and a pharmaceutically acceptable derivative thereof in preparation of an HIV-1 latent infection reversal agent. The Obatoclax has good activity of activating an HIV-1 latent cell bank, is an inhibitor of Bcl-2 family protein, can prevent supplement of the HIV latent cell bank and promote death of reactivated cells, and is expected to realize realfunctional healing of HIV.