Precocious Clonal Hematopoiesis in Down Syndrome is Accompanied by Immune Dysregulation

L. Alexander Liggett,Matthew D. Galbraith,Keith P. Smith,Kelly D. Sullivan,Ross E. Granrath,Belinda Enriquez-Estrada,Kohl T. Kinning,Jessica R. Shaw,Angela L. Rachubinski,Joaquin M. Espinosa,James DeGregori

Blood advances（2021）

引用 11|浏览6

暂无评分

摘要

Key Points Children with Down syndrome develop early signs of clonal evolution that resemble traditional clonal hematopoiesis. Children with trisomy 21 who exhibit clonal hematopoiesis display cytokine and gene expression profiles indicative of disrupted immunity.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要