Thermoacoustic range verification during pencil beam delivery of a clinical plan to an abdominal imaging phantom

Sarah K. Patch,Chinh Nguyen, Diego Dominguez-Ramirez,Rudi Labarbe,Guillaume Janssens, Diego Cammarano, Jake Lister, Christopher Finch,Jamil Lambert, Jeevan Pandey, Christopher Bennett, Elizabeth Porteous, Cezarina Chirvase,Marie Cohilis,Kevin Souris,Shigeto Ono,Ted Lynch

Radiotherapy and Oncology(2021)

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摘要
•Fast (4-6 us) and stress-confined, delivery enables thermoacoustic range verification.•Submillimeter range accuracy was achieved for beamlets that delivered ~0.5 Gy to soft tissue.•Estimates are accurate relative to ultrasound images soundspeed inhomogeneity•Synchrocyclotrons deliver stress-confined proton pulses.•Acoustic ringing indicated beam traversed bone; metallic implants will also cause ringing.
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关键词
Range verification,Ion therapy,Proton therapy,Thermoacoustic,Ionoacoustic
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