Substitution treatment for opioid dependence with slow-release oral morphine: Retention rate, health status, and substance use after switching to morphine

Kirsten Lehmann,Silke Kuhn,Cinzia Baschirotto,Britta Jacobsen,Stephan Walcher,Herbert Görne,Markus Backmund,Norbert Scherbaum,Jens Reimer,Uwe Verthein

Journal of Substance Abuse Treatment（2021）

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摘要

•First long-term data on opioid agonist treatment with SROM in routine care•The retention rate was 61% after twelve months of medication with SROM.•Switching to SROM led to an improvement in mental and physical health.•Alcohol consumption decreased significantly during SROM treatment.•First data on successful switching from levomethadone and buprenorphine to SROM

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关键词

SROM,Slow-release oral morphine,Opioid agonist treatment,Opioid dependence,Treatment retention,Mental health

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