Association Of Cabozantinib Residual Concentration (Ctrough) And Blood Clearance (Cl/F) With Toxicity (Tox) And Progressive Disease (Pd) In Metastatic Renal Cell Carcinoma (Mrcc) Patients (Pts): Results From A Monocentric Pharmacokinetics (Pk) Study.

Luigi Cerbone,David Combarel,Stéphanie Foulon,Arthur Geraud,Carolina Alves,Emeline Colomba,Lucia Carril,Lisa Derosa,Ronan Flippot,Olivier Mir,Bernard Escudier,Angelo Paci,Laurence Albiges

JOURNAL OF CLINICAL ONCOLOGY（2021）

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292Background: Cabozantinib is a TKI with a substantial efficacy in mRCC. It is associated with a relevant tox leading frequent dose modifications (DM) or drug discontinuations (DD). While an expos...

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