Olaparib Efficacy In Patients With Metastatic Castration-Resistant Prostate Cancer (Mcrpc) Carrying Circulating Tumor (Ct) Dna Alterations In Brca1, Brca2 Or Atm: Results From The Profound Study.

Nobuaki Matsubara, Johann S. De Bono,David Olmos,Giuseppe Procopio,Satoru Kawakami,Yuksel Urun,Robbert J. van Alphen, Aude Flechon,Michael Anthony Carducci,Young Deuk Choi,Sebastien J. Hotte,Ernesto Pablo Korbenfeld,Gero Kramer,Neeraj Agarwal,Simon Dearden,Christopher Gresty,Jinyu Kang,Christian Heinrich Poehlein,Elizabeth Harrington,Maha H. A. Hussain

JOURNAL OF CLINICAL ONCOLOGY（2021）

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摘要

27Background: ctDNA testing offers additional opportunities for homologous recombination repair (HRR) gene alteration determination in patients who are not able to access tumor tissue testing. Alte...

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