Stress Degradation Study of Bortezomib: Effect of Co-Solvent, Isolation and Characterization of Degradation Products by UHPLC-Q-TOF-MS/MS and NMR and Evaluation of the Toxicity of the Degradation Products
New journal of chemistry（2021）
摘要
Bortezomib (BTZ) is a first-in-class, potent reversible inhibitor of proteasome used in the treatment of multiple myeloma, the second most common hematological cancer.
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