Synthetic approaches to FDA approved drugs for asthma and COPD from 1969 to 2020.

Ayazoddin Aunoddin Kazi,B V Subba Reddy,L Ravithej Singh

Bioorganic & medicinal chemistry(2021)

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摘要
Respiratory infections resulting from pulmonary inflammation emerging as a leading cause of death worldwide. However, only twenty-seven new drugs were approved in the last five decades. In this review, we presented synthetic approaches for twenty-seven FDA-approved medications used to treat asthma and chronic obstructive pulmonary diseases (COPD), along with their mode of action.
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